Description

tert-Butyl 4-(cyclopropylmethyl)-1,4-diazepane-1-carboxylate is a high-purity, protected diazepane derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, nitrogen-rich scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), especially within the central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological receptors.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing focused libraries and exploring structure-activity relationships (SAR).
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Serves as a starting material for creating tool compounds to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A fundamental building block supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects.

Basic Information

Product Name	tert-Butyl 4-(Cyclopropylmethyl)-1,4-Diazepane-1-Carboxylate
CAS No.	884199-30-8
Molecular Formula	C14H26N2O2
Molecular Weight	254.37 g/mol
Synonyms	1-Boc-4-(cyclopropylmethyl)-1,4-diazepane; 1,4-Diazepane-1-carboxylic acid, 4-(cyclopropylmethyl)-, 1,1-dimethylethyl ester; 4-(Cyclopropylmethyl)-1,4-diazepane-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(cyclopropylmethyl)-1,4-diazepane-1-carboxylate; 1,1-Dimethylethyl 4-(cyclopropylmethyl)-1,4-diazepane-1-carboxylate; Boc-4-(cyclopropylmethyl)-1,4-diazepane
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(cyclopropylmethyl)-1,4-diazepane-1-carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, generated using validated analytical methods including HPLC, GC, and NMR. We are committed to meeting the stringent requirements of our global pharmaceutical and fine chemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.