Description

4-(3-Bromobenzyl)Piperazin-2-One is a high-purity, specialized organic building block featuring a piperazinone core substituted with a 3-bromobenzyl group. This compound is of significant value in pharmaceutical research and development, serving as a key intermediate for the synthesis of novel bioactive molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis to explore new chemical entities with improved potency and selectivity.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides, fungicides, or insecticides.
• Chemical Biology Probes: Utilized in the design and creation of molecular probes for studying enzyme mechanisms or protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.
• Academic Research: Employed in university and institutional labs for methodological development and the exploration of new synthetic pathways.

Basic Information

Product Name	4-(3-Bromobenzyl)Piperazin-2-One
CAS No.	883738-20-3
Molecular Formula	C11H13BrN2O
Molecular Weight	269.14 g/mol
Synonyms	1-(3-Bromobenzyl)piperazin-2-one; 4-(3-Bromobenzyl)-2-piperazinone; 2-Piperazinone, 4-[(3-bromophenyl)methyl]-; 4-(3-Bromobenzyl)-1,4-diazinan-2-one; 4-(3-Bromobenzyl)-2-ketopiperazine; 4-(m-Bromobenzyl)piperazin-2-one; 4-(3-Bromobenzyl)piperazin-2-one; 883738-20-3
EINECS	Contact for details

Quality Control

Our 4-(3-Bromobenzyl)Piperazin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects requiring compliance with various pharmacopeial standards (USP/EP) and can tailor specifications to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.