Description

tert-Butyl (1-(Piperidin-4-Yl)Azetidin-3-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: The piperidine-azetidine core structure is valuable for creating novel enzyme inhibitors.
• Ligand Synthesis for GPCR Targets: Employed in the development of ligands targeting G-protein-coupled receptors, which are prevalent drug targets.
• Chemical Biology Probes: Serves as a starting material for synthesizing tool compounds used to study biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Item	Details
Product Name	tert-Butyl (1-(Piperidin-4-Yl)Azetidin-3-Yl)Carbamate
CAS No.	883546-82-5
Molecular Formula	C13H25N3O2
Molecular Weight	255.36 g/mol
Synonyms	1-Boc-3-(4-piperidyl)azetidine; tert-Butyl 3-(piperidin-4-yl)azetidine-1-carboxylate; 1-(1,1-Dimethylethoxy)carbonyl-3-(4-piperidinyl)azetidine; 3-(Piperidin-4-yl)azetidine-1-carboxylic acid tert-butyl ester; 1-N-Boc-3-(4-piperidyl)azetidine; BOC-3-(4-Piperidyl)azetidine; Azetidine-1-carboxylic acid, 3-(4-piperidinyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (1-(Piperidin-4-Yl)Azetidin-3-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.