Description

1-[1-(2-Hydroxy-3-Piperazin-1-Yl-Propyl)-2,4-Dimethyl-1H-Pyrrol-3-Yl]-Ethanone is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates. The material is supplied under stringent quality control to ensure batch-to-batch consistency for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially for central nervous system (CNS) and receptor-targeted therapies.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new pharmacophores.
• API Development: Serves as a precursor in the multi-step synthesis of complex target molecules for preclinical and clinical trials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for pharmaceutical clients.
• Chemical Reference Standard: Can be used as a high-purity standard for analytical method development and validation in QC laboratories.

Basic Information

Product Name	1-[1-(2-Hydroxy-3-Piperazin-1-Yl-Propyl)-2,4-Dimethyl-1H-Pyrrol-3-Yl]-Ethanone
CAS No.	883543-38-2
Molecular Formula	C15H27N3O2
Molecular Weight	281.40 g/mol
Synonyms	1-[1-(2-Hydroxy-3-piperazin-1-ylpropyl)-2,4-dimethyl-1H-pyrrol-3-yl]ethanone; Ethanone, 1-[1-(2-hydroxy-3-(1-piperazinyl)propyl)-2,4-dimethyl-1H-pyrrol-3-yl]-; 2,4-Dimethyl-1H-pyrrole-3-acetamide derivative; 1-(1-(2-Hydroxy-3-(piperazin-1-yl)propyl)-2,4-dimethyl-1H-pyrrol-3-yl)ethan-1-one; CAS 883543-38-2
EINECS	Contact for details

Quality Control

Our 1-[1-(2-Hydroxy-3-Piperazin-1-Yl-Propyl)-2,4-Dimethyl-1H-Pyrrol-3-Yl]-Ethanone is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high standards required for pharmaceutical research. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can support development with custom purity grades and analytical data packages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.