Description

2-(2,4-Dimethylphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, reactive organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its utility as a versatile building block for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

This specialized acyl chloride derivative serves as a critical precursor in several high-value synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents and pesticides.
• Ligand and Catalyst Development: Serves as a precursor for creating complex chelating ligands used in catalysis and material science.
• Functional Material Research: Employed in the synthesis of organic semiconductors, fluorescent dyes, and other advanced organic electronic materials.
• Custom Chemical Synthesis: A valuable reagent for contract research organizations (CROs) and CDMOs for producing bespoke compounds and libraries.

Basic Information

Product Name	2-(2,4-Dimethylphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	883526-18-9
Molecular Formula	C18H14ClNO
Molecular Weight	295.76 g/mol
Synonyms	2-(2,4-Dimethylphenyl)-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(2,4-dimethylphenyl)-; 2-(2,4-Dimethylphenyl)quinoline-4-carboxylic acid chloride; Quinoline-4-carbonyl chloride, 2-(2,4-dimethylphenyl)-; 883526-18-9; 2,4-Dimethylphenylquinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-(2,4-Dimethylphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and strong bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.