Description

2-(4-Benzyl-1-Piperazino)-3-Fluoro-Benzaldehyde is a high-purity, advanced pharmaceutical intermediate featuring a benzaldehyde core substituted with a fluorinated aromatic ring and a benzylpiperazine moiety. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, custom synthesis providers, and manufacturers of active pharmaceutical ingredients (APIs) seeking to develop new chemical entities with enhanced biological activity and selectivity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and pharmacokinetic properties of lead compounds.
• Custom Synthesis: Serves as a starting material or intermediate for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.
• Active Pharmaceutical Ingredient (API) Development: Incorporated into the synthetic route of potential APIs during preclinical and early-phase development.
• Chemical Library Synthesis: Used to create diverse compound libraries for high-throughput screening in drug discovery programs.
• Academic Research: Employed in university and institutional labs for investigating new organic reactions and heterocyclic chemistry.

Basic Information

Product Name	2-(4-Benzyl-1-Piperazino)-3-Fluoro-Benzaldehyde
CAS No.	883512-18-3
Molecular Formula	C18H19FN2O
Molecular Weight	298.36 g/mol
Synonyms	3-Fluoro-2-(4-benzylpiperazin-1-yl)benzaldehyde; 2-(4-Benzylpiperazin-1-yl)-3-fluorobenzaldehyde; 3-Fluoro-2-(4-benzyl-1-piperazinyl)benzaldehyde; Benzaldehyde, 2-(4-benzyl-1-piperazinyl)-3-fluoro-; 883512-18-3; 2-(4-Benzylpiperazino)-3-fluorobenzaldehyde; 3-Fluoro-2-(N-benzylpiperazino)benzaldehyde
EINECS	Contact for details

Quality Control

Our 2-(4-Benzyl-1-Piperazino)-3-Fluoro-Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.