Description

trans-1-Amino-4-(4-Methyl-1-piperazino)cyclohexane is a high-purity, functionalized cyclohexylamine derivative featuring both a primary amine and a methylpiperazine moiety. This unique bifunctional structure makes it a valuable and versatile pharmaceutical intermediate and organic building block for advanced synthesis. It is primarily utilized in research and development for creating novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. The compound's defined stereochemistry and functional groups offer precise control in constructing target molecules for the life sciences industry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex amines, heterocycles, and chiral auxiliaries in medicinal chemistry.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed reactions or as a component in catalyst design.
• Bioconjugation and Linker Chemistry: The primary amine group enables its use in creating chemical linkers for antibody-drug conjugates (ADCs) or other bioconjugation applications.
• Agrochemical Research: Intermediate in the development of new crop protection agents and pesticides requiring specific amine functionalities.
• Material Science: Potential monomer or cross-linking agent in the synthesis of specialty polymers and advanced materials.

Basic Information

Item	Details
Product Name	trans-1-Amino-4-(4-Methyl-1-piperazino)cyclohexane
CAS No.	883195-08-2
Molecular Formula	C11H23N3
Molecular Weight	197.32 g/mol
Synonyms	trans-4-Amino-1-(4-methylpiperazin-1-yl)cyclohexane; 1-Piperazinecyclohexanamine, 4-methyl-, trans-; 4-(4-Methylpiperazin-1-yl)cyclohexan-1-amine (trans); trans-4-(4-Methyl-1-piperazinyl)cyclohexylamine; trans-N1-(4-Methylpiperazin-1-yl)cyclohexane-1,4-diamine; (1r,4r)-4-(4-Methylpiperazin-1-yl)cyclohexan-1-amine; CAS 883195-08-2
EINECS	Contact for details

Quality Control

Every batch of trans-1-Amino-4-(4-Methyl-1-piperazino)cyclohexane is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are supported by a detailed Certificate of Analysis (COA) that includes results from HPLC, NMR, and other relevant spectroscopic methods. We adhere to cGMP principles where applicable to support its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
trans-Isomer Content (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.