Description

1-(Cyclopropylcarbonyl)-4-Piperidinamine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its role as a key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. This compound is essential for medicinal chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries seeking to develop new drug candidates.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Process Chemistry Development: Serves as a key starting material (KSM) or advanced intermediate in the scale-up and optimization of API manufacturing routes.
• Bioconjugation & Probe Synthesis: Utilized in the creation of chemical probes for biological target identification and validation in drug discovery.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.
• Academic Research: Employed in university and institutional labs for fundamental organic synthesis and pharmacological studies.

Basic Information

Item	Detail
Product Name	1-(Cyclopropylcarbonyl)-4-Piperidinamine Hydrochloride
CAS No.	883106-47-6
Molecular Formula	C9H17ClN2O
Molecular Weight	204.70 g/mol
Synonyms	4-Amino-1-(cyclopropylcarbonyl)piperidine hydrochloride; 1-(Cyclopropylcarbonyl)piperidin-4-amine hydrochloride; 4-Piperidinamine, 1-(cyclopropylcarbonyl)-, hydrochloride (1:1); 1-Cyclopropylcarbonyl-4-piperidinamine HCl; Piperidin-4-amine, 1-(cyclopropylcarbonyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Cyclopropylcarbonyl)-4-Piperidinamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.