Description

(E)-2-[(4-Chlorophenyl)Sulfonyl]-3-(4-Phenylpiperazino)-2-Propenenitrile is a specialized organic intermediate featuring a unique sulfonyl and piperazine-based molecular architecture. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical candidates and high-value fine chemicals. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for creating novel molecules with targeted biological or functional properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological or metabolic disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, or insecticides, leveraging its sulfonyl and nitrile functional groups.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of advanced polymers with specific optical or electronic properties.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme inhibition or protein-ligand interactions due to its potential reactive sites.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for producing complex, high-value specialty chemicals.

Basic Information

Product Name	(E)-2-[(4-Chlorophenyl)Sulfonyl]-3-(4-Phenylpiperazino)-2-Propenenitrile
CAS No.	883003-06-3
Molecular Formula	C19H18ClN3O2S
Molecular Weight	387.88 g/mol
Synonyms	2-[(4-Chlorophenyl)sulfonyl]-3-(4-phenyl-1-piperazinyl)-2-propenenitrile; (E)-2-((4-Chlorophenyl)sulfonyl)-3-(4-phenylpiperazin-1-yl)acrylonitrile; Propenenitrile, 2-[(4-chlorophenyl)sulfonyl]-3-(4-phenyl-1-piperazinyl)-, (E)-; 883003-06-3; (E)-2-(4-Chlorobenzenesulfonyl)-3-(4-phenylpiperazino)acrylonitrile; Acrylonitrile derivative CAS 883003-06-3
EINECS	Contact for details

Quality Control

Our (E)-2-[(4-Chlorophenyl)Sulfonyl]-3-(4-Phenylpiperazino)-2-Propenenitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.