Description

Fmoc-18-Amino-4,7,10,13,16-Pentaoxaoctadecanoic Acid is a specialized, high-purity building block designed for solid-phase peptide synthesis (SPPS). Its core value lies in the unique, long-chain hydrophilic spacer it introduces, which is critical for improving the solubility and bioavailability of synthetic peptides. This compound is essential for researchers and manufacturers in pharmaceutical development, bioconjugation, and the production of peptide-based therapeutics and diagnostics.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected amino acid derivative for the controlled assembly of complex peptide sequences.
• PEGylation & Linker Chemistry: Serves as a versatile, hydrophilic spacer arm (incorporating a pentaethylene glycol chain) for conjugating peptides to other molecules, surfaces, or reporter groups.
• Pharmaceutical R&D: Key intermediate in the development of peptide drugs where enhanced solubility and reduced aggregation are required.
• Bioconjugation Probes: Used to create labeled peptides for diagnostic assays, imaging, and targeted drug delivery systems.
• Material Science: Functionalization of surfaces and biomaterials with bioactive peptide motifs.

Basic Information

Product Name	Fmoc-18-Amino-4,7,10,13,16-Pentaoxaoctadecanoic Acid
CAS No.	882847-32-7
Molecular Formula	C33H47NO11
Molecular Weight	633.73 g/mol
Synonyms	Fmoc-NH-PEG5-CH2CH2COOH; Fmoc-18-amino-4,7,10,13,16-pentaoxaoctadecanoic acid; N-α-Fmoc-18-amino-4,7,10,13,16-pentaoxaoctadecanoic acid; Fmoc-PEG5-acid; Fmoc-Amino-PEG5-Acid; 2-{2-[2-(2-{2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]ethoxy}ethoxy)ethoxy]ethoxy}acetic acid; Fmoc-N-amido-PEG5-acid
EINECS	Contact for details

Quality Control

Our Fmoc-18-Amino-4,7,10,13,16-Pentaoxaoctadecanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C. This product is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.