Description

Cyclohexanamine, 4-[4-(cyclopropylmethyl)-1-piperazinyl]-, (hydrochloride) (1:3), trans- is a high-purity, specialized organic salt with a defined stereochemistry. This compound is valued for its role as a key synthetic intermediate in advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel therapeutic compounds, particularly in central nervous system (CNS) and other specialized drug discovery programs.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling the exploration of structure-activity relationships (SAR) and the creation of new chemical entities.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for potential active pharmaceutical ingredients (APIs) during pre-clinical and clinical development phases.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical manufacturing.
• Academic Research: Employed in university and institutional laboratories for studies in organic synthesis, pharmacology, and chemical biology.

Basic Information

Product Name	Cyclohexanamine, 4-[4-(cyclopropylmethyl)-1-piperazinyl]-, (hydrochloride) (1:3), trans-
CAS No.	882660-42-6
Molecular Formula	C14H27N3 · 3HCl
Molecular Weight	367.21 g/mol (Free base: 237.39 g/mol)
Synonyms	trans-4-[4-(Cyclopropylmethyl)piperazin-1-yl]cyclohexanamine trihydrochloride; trans-N1-[4-(Cyclopropylmethyl)piperazin-1-yl]cyclohexane-1,4-diamine trihydrochloride; (1r,4r)-4-[4-(Cyclopropylmethyl)piperazin-1-yl]cyclohexanamine trihydrochloride; BRN 882660-42-6; trans-Cyclohexanamine, 4-[4-(cyclopropylmethyl)-1-piperazinyl]-, trihydrochloride; 4-(4-Cyclopropylmethyl-piperazin-1-yl)-cyclohexylamine trihydrochloride, trans-
EINECS	Contact for details

Quality Control

Our Cyclohexanamine, 4-[4-(cyclopropylmethyl)-1-piperazinyl]-, (hydrochloride) (1:3), trans- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis to confirm stereochemistry, and identification by IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% trans-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.