Description

2-(4-Aminopiperidin-1-Yl)-n-Methylacetamide Dihydrochloride is a high-purity, pharmaceutically relevant intermediate and building block. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in drug discovery programs, particularly those focused on central nervous system (CNS) and metabolic disease targets.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic agents.
• API Synthesis: Serves as a precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis and pharmacology.

Basic Information

Product Name	2-(4-Aminopiperidin-1-Yl)-n-Methylacetamide Dihydrochloride
CAS No.	882562-64-3
Molecular Formula	C8H18N3O • 2HCl
Molecular Weight	269.17 g/mol (as free base: 169.25 g/mol)
Synonyms	1-[2-(Methylamino)-2-oxoethyl]-4-piperidinamine dihydrochloride; N-Methyl-2-(4-aminopiperidin-1-yl)acetamide dihydrochloride; 4-Amino-1-(N-methylcarbamoylmethyl)piperidinium dichloride; 2-(4-Amino-1-piperidinyl)-N-methylacetamide dihydrochloride; 882562-64-3; UNII-9J6I9Q8F1M; 9J6I9Q8F1M
EINECS	Contact for details

Quality Control

Our 2-(4-Aminopiperidin-1-Yl)-n-Methylacetamide Dihydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) compliance for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.