Description

2-Bromo-4,4,4-Trifluorobutyric Acid is a versatile fluorinated organic acid building block, essential for introducing both bromine and trifluoromethyl functionalities into target molecules. Its unique structure makes it a critical intermediate for the synthesis of advanced pharmaceuticals, agrochemicals, and specialty materials. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially those requiring trifluoromethyl groups for improved lipophilicity and metabolic resistance.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the bromine atom allows for further functionalization.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for fluorinated components in electronic display technologies and organic light-emitting diodes.
• Fluorinated Surfactant & Polymer Modification: Employed to introduce fluorine into polymers and surfactants, enhancing properties like oil repellency, chemical resistance, and thermal stability.
• Cross-Coupling Reactions: The bromine substituent makes it a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex molecular architectures.
• Research & Development: A valuable reagent in medicinal chemistry and material science R&D for exploring new chemical entities and fluorinated compounds.

Basic Information

Product Name	2-Bromo-4,4,4-Trifluorobutyric Acid
CAS No.	882050-69-3
Molecular Formula	C4H4BrF3O2
Molecular Weight	221.97 g/mol
Synonyms	2-Bromo-4,4,4-trifluorobutanoic Acid; 4,4,4-Trifluoro-2-bromobutyric Acid; α-Bromo-γ,γ,γ-trifluorobutyric Acid; Butyric acid, 2-bromo-4,4,4-trifluoro-; 2-Bromo-4,4,4-trifluoro-butanoic acid; 2-Br-4,4,4-F3-butyric acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-4,4,4-Trifluorobutyric Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.