Description

Jnj 26854165 Dihydrochloride is a high-purity, small molecule compound of significant interest in pharmaceutical research and development. This material serves as a critical intermediate and reference standard for the synthesis and biological evaluation of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical companies, and contract research organizations (CROs) engaged in oncology and targeted drug discovery programs.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Biochemical Assay Standard: Used as a reference standard in high-throughput screening (HTS) and in-vitro biological activity studies.
• Oncology Research: Employed in preclinical studies targeting specific biological pathways relevant to cancer therapy.
• Academic Research: Utilized in university and institutional labs for fundamental chemical and pharmacological studies.
• Contract Manufacturing: Sourced by CMOs for the cGMP or non-GMP production of clinical trial materials.
• Analytical Method Development: Serves as a system suitability standard for HPLC, LC-MS, and other analytical techniques.

Basic Information

Product Name	Jnj 26854165 Dihydrochloride
CAS No.	881202-16-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	JNJ-26854165 dihydrochloride; 26854165 Dihydrochloride; JNJ 26854165 HCl; Serdemetan dihydrochloride; (S)-N-(4-(3-(4-(3,4-Dihydro-6,7-dimethoxyisoquinolin-2(1H)-yl)-2-hydroxypropoxy)phenyl)thiazol-2-yl)acetamide dihydrochloride; UNII-1W8KQ0H1V5; JNJ26854165 dihydrochloride
EINECS	Contact for details

Quality Control

Our Jnj 26854165 Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods, and residual solvent analysis to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.