Description

(7R,8As)-Octahydropyrrolo[1,2-A]Pyrazin-7-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and fused bicyclic structure. This compound is of significant value for its role as a key chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in developing novel therapeutics, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the multi-step synthesis of potential drug candidates, especially those targeting the central nervous system.
• Organic Synthesis Building Block: Used in research and development for constructing complex nitrogen-containing heterocycles due to its pyrrolopyrazine core.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes to explore new biological activities.
• Asymmetric Synthesis: Utilized in reactions where its defined stereocenters (7R,8As) are crucial for inducing chirality in final target molecules.
• Process Chemistry Development: Acts as a starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	(7R,8As)-Octahydropyrrolo[1,2-A]Pyrazin-7-Ol
CAS No.	879399-07-2
Molecular Formula	C7H12N2O
Molecular Weight	140.18 g/mol
Synonyms	(7R,8aS)-Octahydro-1H-pyrrolo[1,2-a]pyrazin-7-ol; (7R,8aS)-Octahydropyrrolo[1,2-a]pyrazin-7-ol; Pyrrolo[1,2-a]pyrazin-7-ol, octahydro-, (7R,8aS)-; (7R,8aS)-Octahydro-1H-pyrrolo[1,2-a]pyrazine-7-ol; 879399-07-2; UNII-7J8J22L1QN
EINECS	Contact for details

Quality Control

Our (7R,8As)-Octahydropyrrolo[1,2-A]Pyrazin-7-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.