Description

5,6,7,8-Tetrahydro-2-[4-(4-Methoxyphenyl)-1-Piperazinyl]-4(3H)-Quinazolinone is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinone class of heterocyclic compounds. This compound is of significant value in medicinal chemistry research and development, particularly for its role as a key building block in synthesizing novel therapeutic agents. It is primarily sought after by R&D laboratories, pharmaceutical manufacturers, and CROs (Contract Research Organizations) engaged in the discovery of new drugs targeting central nervous system and other disorders.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those with potential neurological activity.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in in-vitro assays to study interactions with biological targets such as enzymes and receptors.
• Process Development: Used in scaling up and optimizing synthetic routes for potential active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	5,6,7,8-Tetrahydro-2-[4-(4-Methoxyphenyl)-1-Piperazinyl]-4(3H)-Quinazolinone
CAS No.	878433-57-9
Molecular Formula	C19H22N4O2
Molecular Weight	338.41 g/mol
Synonyms	2-[4-(4-Methoxyphenyl)piperazin-1-yl]-5,6,7,8-tetrahydroquinazolin-4(3H)-one; 5,6,7,8-Tetrahydro-2-(4-(4-methoxyphenyl)piperazin-1-yl)quinazolin-4(3H)-one; THQ-MPP; Quinazolinone piperazine derivative; CAS 878433-57-9
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-2-[4-(4-Methoxyphenyl)-1-Piperazinyl]-4(3H)-Quinazolinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from moisture and direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.