Description

3-Oxopiperazine-1-Sulfonamide is a high-purity, advanced pharmaceutical intermediate characterized by its sulfonamide and piperazine-based heterocyclic structure. This compound is of significant commercial interest for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for central nervous system (CNS) and anti-infective agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological disorders.
• Protease Inhibitor Research: Used in the development of inhibitors for various enzymatic targets due to its sulfonamide moiety.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening (HTS) campaigns.
• API Process Development: Employed in route scouting and optimization studies for the commercial-scale production of new chemical entities.
• Bioconjugation & Linker Chemistry: Potential use in creating drug-linker systems for antibody-drug conjugates (ADCs) or other targeted therapies.

Basic Information

Product Name	3-Oxopiperazine-1-Sulfonamide
CAS No.	878386-22-2
Molecular Formula	C4H7N3O3S
Molecular Weight	177.18 g/mol
Synonyms	1-Sulfamoylpiperazin-2-one; 2-Oxo-1-piperazinesulfonamide; Piperazine-1-sulfonamide, 3-oxo-; 3-Oxo-1-piperazinesulfonamide; 1-Piperazinesulfonamide, 3-oxo-; 3-Oxopiperazine-1-sulfonic acid amide
EINECS	Contact for details

Quality Control

Our 3-Oxopiperazine-1-Sulfonamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.