Description

tert-Butyl 4-(Cyanomethyl)-4-(4-Methoxyphenyl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a protected piperidine scaffold. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapies. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in novel drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potent, selective receptor modulators and enzyme inhibitors.
• Drug Discovery & Medicinal Chemistry: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Process Chemistry & Scale-Up: Serves as a critical intermediate in the development of robust, scalable synthetic routes for API manufacturing.
• Neurological & Psychiatric Drug Research: Found in synthetic pathways for compounds targeting serotonin, dopamine, or other neurotransmitter systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific novel chemical entities (NCEs).
• Academic & Institutional Research: Used in chemical biology and pharmacology research to explore new biological mechanisms.

Basic Information

Product Name	tert-Butyl 4-(Cyanomethyl)-4-(4-Methoxyphenyl)Piperidine-1-Carboxylate
CAS No.	878130-38-2
Molecular Formula	C19H26N2O3
Molecular Weight	330.43 g/mol
Synonyms	1-Boc-4-(cyanomethyl)-4-(4-methoxyphenyl)piperidine; 4-(Cyanomethyl)-4-(4-methoxyphenyl)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(cyanomethyl)-4-(4-methoxyphenyl)piperidine; tert-Butyl 4-(cyanomethyl)-4-(p-methoxyphenyl)piperidine-1-carboxylate; 4-(4-Methoxyphenyl)-4-(cyanomethyl)piperidine-1-carboxylic acid tert-butyl ester; BOC-4-(Cyanomethyl)-4-(4-methoxyphenyl)piperidine; 878130-38-2
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(Cyanomethyl)-4-(4-Methoxyphenyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.