Description

S-4-Oxide-4-Hydroxy-2,6-Bis(2,4,6-Trimethylphenyl)-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin is a sophisticated organophosphorus compound with a unique dinaphthodioxaphosphepin core structure, valued for its role as a chiral ligand or catalyst precursor in advanced synthetic chemistry. This compound matters for enabling highly selective and efficient catalytic transformations, particularly in the synthesis of complex, high-value molecules where stereochemical control is paramount. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and materials science.

Application

• Asymmetric Catalysis: Serving as a chiral ligand or precursor for metal complexes used in enantioselective C-C and C-X bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Facilitating the production of optically active intermediates for active pharmaceutical ingredients (APIs).
• Agrochemical Research: Enabling the development of novel, stereochemically defined pesticides and herbicides.
• Material Science: Potential use in the synthesis of chiral polymers or advanced organic frameworks with specific optical properties.
• Academic & Industrial R&D: A key reagent for methodological development in organic and organometallic chemistry research.
• Fine Chemical Production: Application in the custom synthesis of complex, high-purity specialty chemicals.

Basic Information

Product Name	S-4-Oxide-4-Hydroxy-2,6-Bis(2,4,6-Trimethylphenyl)-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin
CAS No.	878111-18-3
Molecular Formula	C44H37O4P
Molecular Weight	660.74 g/mol
Synonyms	S-4-Oxido-4-hydroxy-2,6-bis(2,4,6-trimethylphenyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin; (S)-4-Hydroxy-2,6-bis(2,4,6-trimethylphenyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin 4-oxide; S-BINAP(O)OH derivative; Chiral dinaphthodioxaphosphepin oxide; S-BINOL-based phosphite oxide; (S)-H8-BINAP(O)OH analog; Ligand L*-P(O)OH; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our production of S-4-Oxide-4-Hydroxy-2,6-Bis(2,4,6-Trimethylphenyl)-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity, critical for catalytic performance. All materials are characterized by advanced analytical techniques including NMR, HPLC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and related substances is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept tightly sealed under an inert atmosphere to prevent degradation and moisture uptake. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.