Description

1-Piperazinecarboxylic Acid, 4-[4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]Butyl]-, Phenylmethyl Ester is a sophisticated, high-purity chemical intermediate designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring precise molecular architecture in complex organic syntheses. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and cardiovascular pathways.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its piperazine core for biological activity.
• Peptide Mimetics & Drug Discovery: Serves as a crucial scaffold in medicinal chemistry for creating peptide-like molecules and probing structure-activity relationships (SAR).
• Custom Synthesis & Contract Manufacturing: An essential reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals.
• Bioconjugation & Linker Chemistry: The protected functional groups make it valuable for creating cleavable linkers in antibody-drug conjugates (ADCs) and other bioconjugation strategies.
• Academic & Institutional Research: Employed in university and institutional labs for fundamental organic chemistry research and the development of new synthetic methodologies.

Basic Information

Product Name	1-Piperazinecarboxylic Acid, 4-[4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]Butyl]-, Phenylmethyl Ester
CAS No.	877664-86-3
Molecular Formula	C21H33N3O4
Molecular Weight	391.51 g/mol
Synonyms	4-(4-((tert-Butoxycarbonyl)amino)butyl)piperazine-1-carboxylic acid benzyl ester; Benzyl 4-(4-((tert-butoxycarbonyl)amino)butyl)piperazine-1-carboxylate; N-Boc-4-(4-(piperazin-1-yl)butyl)carbamate benzyl ester; 1-Piperazinecarboxylic acid, 4-[4-[[(1,1-dimethylethoxy)carbonyl]amino]butyl]-, phenylmethyl ester; Boc-4-Aminobutyl-piperazine-1-carboxylic acid benzyl ester; tert-Butyl (4-(4-(benzyloxycarbonyl)piperazin-1-yl)butyl)carbamate
EINECS	Contact for details

Quality Control

Our production of 1-Piperazinecarboxylic Acid, 4-[4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]Butyl]-, Phenylmethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for sensitive applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.