Description

4-Chloro-2-Trifluoromethylpyrazolo[1.5-A]Pyrazine is a high-value, multi-functional heterocyclic building block containing both chlorine and trifluoromethyl substituents. This compound is essential for advanced research and development in medicinal chemistry, enabling the rapid synthesis of novel drug candidates. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the discovery and development of new-generation pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a specialized monomer or precursor for developing advanced functional materials, such as organic semiconductors or liquid crystals.
• Medicinal Chemistry Scaffold: Provides a privileged heterocyclic core for constructing compound libraries via parallel synthesis and combinatorial chemistry for high-throughput screening.
• Fluorine Chemistry Building Block: Utilized in organofluorine chemistry to introduce the valuable CF3 group into complex molecular architectures, improving lipophilicity and bioavailability.

Basic Information

Product Name	4-Chloro-2-Trifluoromethylpyrazolo[1.5-A]Pyrazine
CAS No.	877402-79-4
Molecular Formula	C7H3ClF3N3
Molecular Weight	221.57 g/mol
Synonyms	4-Chloro-2-(trifluoromethyl)pyrazolo[1,5-a]pyrazine; 4-Chloro-2-trifluoromethyl-pyrazolo[1,5-a]pyrazine; 4-Chloro-2-(trifluoromethyl)pyrazolo[1,5-a]pyrazine; Pyrazolo[1,5-a]pyrazine, 4-chloro-2-(trifluoromethyl)-; 877402-79-4; 4-Chloro-2-trifluoromethylpyrazolo[1,5-a]pyrazine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Trifluoromethylpyrazolo[1.5-A]Pyrazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC-MS for impurity profiling. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.