Description

4-(4-Bromopyrazol-1-Yl)Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a versatile building block for the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for drug discovery programs.
• Kinase Inhibitor Development: Serves as a core scaffold or precursor in the creation of novel kinase inhibitor candidates.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.

Basic Information

Product Name	4-(4-Bromopyrazol-1-Yl)Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	877399-50-3
Molecular Formula	C13H20BrN3O2
Molecular Weight	330.22 g/mol
Synonyms	1-Boc-4-(4-bromo-1H-pyrazol-1-yl)piperidine; tert-Butyl 4-(4-bromo-1H-pyrazol-1-yl)piperidine-1-carboxylate; 4-(4-Bromo-1H-pyrazol-1-yl)-1-(tert-butoxycarbonyl)piperidine; 1-(tert-Butoxycarbonyl)-4-(4-bromopyrazol-1-yl)piperidine; 4-(4-Bromo-pyrazol-1-yl)-piperidine-1-carboxylic acid tert-butyl ester; 877399-50-3; 4-(4-Bromopyrazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 4-(4-Bromopyrazol-1-Yl)Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.