Description

3-(2-Ethoxycarbonyl-Acetyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine and tert-butyl ester functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering a versatile building block for medicinal chemistry research and process development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up API manufacturing processes.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule assembly.
• Protease Inhibitor Synthesis: Potential precursor in the development of protease inhibitor类药物, a class of important therapeutic agents.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development and quality control in API production.

Basic Information

Product Name	3-(2-Ethoxycarbonyl-Acetyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	877173-80-3
Molecular Formula	C15H25NO5
Molecular Weight	299.36 g/mol
Synonyms	1-Boc-3-(2-ethoxycarbonylacetyl)piperidine; tert-Butyl 3-(2-ethoxy-2-oxoacetyl)piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-(2-ethoxy-2-oxoacetyl)piperidine; 3-(2-Ethoxy-2-oxoacetyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 877173-80-3; 3-(2-Ethoxycarbonylacetyl)-1-Boc-piperidine; 1-Boc-3-(ethoxyoxalyl)piperidine
EINECS	Contact for details

Quality Control

Our 3-(2-Ethoxycarbonyl-Acetyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.