Description

2-Bromo-7-Iodo-5-Tosyl-5H-Pyrrolo[2,3-B]Pyrazine is a high-value, multi-halogenated heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for medicinal chemistry research and pharmaceutical development, serving as a versatile intermediate for constructing complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries to introduce specific halogenated pyrrolopyrazine motifs into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its reactive halogen sites for cross-coupling reactions.
• Agrochemical Synthesis: Intermediate in the development of novel active ingredients for crop protection products.
• Chemical Biology Probes: Serves as a precursor for labeled compounds or probes used in biochemical and cellular assays.
• Material Science: Potential monomer or precursor for functional organic materials and electronic chemicals.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development-scale batches.

Basic Information

Product Name	2-Bromo-7-Iodo-5-Tosyl-5H-Pyrrolo[2,3-B]Pyrazine
CAS No.	875781-45-6
Molecular Formula	C13H9BrIN3O2S
Molecular Weight	477.10 g/mol
Synonyms	5H-Pyrrolo[2,3-b]pyrazine, 2-bromo-7-iodo-5-[(4-methylphenyl)sulfonyl]-; 2-Bromo-7-iodo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine; 2-Bromo-7-iodo-5-(p-tolylsulfonyl)-5H-pyrrolo[2,3-b]pyrazine; 5-Tosyl-2-bromo-7-iodo-5H-pyrrolo[2,3-b]pyrazine; CAS 875781-45-6
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-7-Iodo-5-Tosyl-5H-Pyrrolo[2,3-B]Pyrazine is synthesized and purified under controlled conditions to ensure high chemical purity and lot-to-lot consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is likely light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.