Description

1-Methyl-3-Azetidinecarboxylic Acid is a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and agrochemicals, enabling the introduction of the constrained azetidine ring system. Pharmaceutical researchers and fine chemical manufacturers need it for constructing complex molecules, particularly in medicinal chemistry programs targeting new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing the azetidine moiety, which is valued for its metabolic stability and conformational restriction.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the azetidine ring can enhance biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the synthesis of novel polymers and functional materials with specific thermal or mechanical properties derived from the rigid azetidine structure.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways, leveraging its ability to mimic natural amino acid structures.

Basic Information

Product Name	1-Methyl-3-Azetidinecarboxylic Acid
CAS No.	875629-26-8
Molecular Formula	C5H9NO2
Molecular Weight	115.13 g/mol
Synonyms	1-Methylazetidine-3-carboxylic Acid; 3-Azetidinecarboxylic Acid, 1-methyl-; 1-Methyl-3-carboxyazetidine; Azetidine-3-carboxylic acid, 1-methyl-; 1-Methylazetidine-3-carboxylic acid; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 1-Methyl-3-Azetidinecarboxylic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.