Description

S-3,3'-Bis(Phenyl)-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate is a chiral phosphoric acid derivative, a key member of the BINOL-phosphate family of organocatalysts. This compound matters for its role as a highly effective and enantioselective Brønsted acid catalyst in asymmetric synthesis. It is essential for researchers and process chemists in the pharmaceutical and fine chemical industries who require precise stereochemical control for creating chiral intermediates and active pharmaceutical ingredients (APIs).

Application

• As a chiral Brønsted acid catalyst in asymmetric synthesis and organocatalysis.
• Enantioselective Mannich reactions, Friedel-Crafts alkylations, and transfer hydrogenations.
• Key reagent for the synthesis of chiral pharmaceutical intermediates and natural products.
• Used in the preparation of optically active compounds for agrochemical and material science research.
• Facilitates carbon-carbon and carbon-heteroatom bond-forming reactions with high stereoselectivity.
• Employed in academic and industrial R&D for developing new catalytic methodologies.

Basic Information

Product Name	S-3,3'-Bis(Phenyl)-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate
CAS No.	874948-59-1
Molecular Formula	C32H21O4P
Molecular Weight	500.48 g/mol
Synonyms	(S)-3,3'-Diphenyl-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; (S)-TRIP; (S)-3,3'-Bis(3,4,5-triphenylphenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate (common trade name context); (S)-Ph-BINOL Phosphoric Acid; (S)-3,3'-Diphenyl-BINOL Phosphoric Acid; (S)-VAPOL Phosphoric Acid derivative; Chiral Phosphoric Acid Catalyst; S-BINOL-Derived Phosphoric Acid
EINECS	Contact for details

Quality Control

Our S-3,3'-Bis(Phenyl)-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and chiral purity, NMR for structural confirmation, and ICP-MS for trace metal screening. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect catalytic activity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.