Description

1-(4-Boc-Aminobutyl)Piperazine is a high-purity, protected amine derivative used as a critical building block in advanced organic synthesis. This compound is essential for the controlled introduction of a piperazine moiety with a Boc-protected aminoalkyl linker, enabling the construction of complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and biotechnology sectors for applications such as drug discovery, peptide mimetics, and the synthesis of functionalized polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and as a linker for antibody-drug conjugates (ADCs).
• Peptide & Peptidomimetic Synthesis: Serves as a versatile spacer or functional group for modifying peptide backbones and creating novel peptidomimetic compounds with enhanced stability and bioavailability.
• Ligand & Catalyst Development: Used to synthesize chelating ligands for metal catalysts or as a functional handle for immobilizing catalysts on solid supports.
• Polymer & Material Science: Incorporated into polymer chains to introduce tertiary amine functionality, modifying material properties for specialized coatings, adhesives, or drug delivery systems.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Agrochemical Research: Acts as a building block for novel crop protection agents and herbicides, leveraging its structural features for bioactivity.

Basic Information

Product Name	1-(4-Boc-Aminobutyl)Piperazine
CAS No.	874831-61-5
Molecular Formula	C13H27N3O2
Molecular Weight	257.37 g/mol
Synonyms	1-(4-((tert-Butoxycarbonyl)amino)butyl)piperazine; tert-Butyl N-(4-(piperazin-1-yl)butyl)carbamate; 4-(Piperazin-1-yl)butan-1-amine, N-Boc derivative; N-Boc-1,4-diaminobutane piperazine derivative; Boc-4-aminobutylpiperazine; 1-(4-(Boc-amino)butyl)piperazine; 874831-61-5; N-(tert-Butoxycarbonyl)-4-(piperazin-1-yl)butan-1-amine
EINECS	Contact for details

Quality Control

Our 1-(4-Boc-Aminobutyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.