Description

tert-Butyl 4-(4-Fluoro-2-Nitrophenyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine core and nitro-fluorophenyl substituent. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• API Development: Integral in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) with fluorinated aromatic systems.
• Chemical Biology Probes: Serves as a starting material for creating labeled compounds or probes used in biochemical and cellular assays.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects on a gram to kilogram scale.

Basic Information

Product Name	tert-Butyl 4-(4-Fluoro-2-Nitrophenyl)Piperazine-1-Carboxylate
CAS No.	874814-94-5
Molecular Formula	C15H20FN3O4
Molecular Weight	325.34 g/mol
Synonyms	1-Boc-4-(4-Fluoro-2-nitrophenyl)piperazine; tert-Butyl 4-(4-fluoro-2-nitrophenyl)-1-piperazinecarboxylate; 4-(4-Fluoro-2-nitrophenyl)piperazine-1-carboxylic acid tert-butyl ester; N-Boc-4-(4-fluoro-2-nitrophenyl)piperazine; 874814-94-5; 1-Piperazinecarboxylic acid, 4-(4-fluoro-2-nitrophenyl)-, 1,1-dimethylethyl ester; Boc-4-(4-Fluoro-2-nitro-phenyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Fluoro-2-Nitrophenyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.