Description

Gpr40/Ffar1 Modulator 1 is a high-purity, small-molecule research compound designed for pharmacological and biochemical studies. This compound serves as a selective modulator of the G-protein-coupled receptor 40 (GPR40), also known as Free Fatty Acid Receptor 1 (FFAR1), a key target in metabolic disease research. It is essential for researchers and pharmaceutical developers in the fields of type 2 diabetes, obesity, and metabolic syndrome, providing a critical tool for target validation and drug discovery programs.

Application

• Pharmacological Research: Used as a reference standard and active probe in studies investigating GPR40/FFAR1 receptor signaling pathways and physiology.
• Drug Discovery & Development: Serves as a key intermediate or lead compound in the synthesis and optimization of novel therapeutics targeting metabolic disorders.
• Biochemical Assays: Employed in high-throughput screening (HTS), binding assays, and functional cellular assays to evaluate receptor activity and compound efficacy.
• Academic & Institutional Research: Utilized in university and research institute labs for fundamental studies on insulin secretion, pancreatic β-cell function, and energy homeostasis.
• Preclinical Studies: Applied in animal model research to investigate the in vivo effects of GPR40 modulation on glucose tolerance and lipid metabolism.

Basic Information

Product Name	Gpr40/Ffar1 Modulator 1
CAS No.	874755-26-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	FFAR1 Modulator 1; GPR40 Modulator 1; GPR40/FFAR1 Agonist; 874755-26-7; Free Fatty Acid Receptor 1 Modulator; TAK-875 analog; Fasiglifam related compound; G-protein-coupled receptor 40 agonist
EINECS	Contact for details

Quality Control

Our Gpr40/Ffar1 Modulator 1 is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for critical research. Each lot undergoes comprehensive analytical characterization, including purity verification by HPLC and structural confirmation. A Certificate of Analysis (COA) detailing identity, purity, and analytical methods is provided with every shipment to support your regulatory and documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under inert atmosphere for long-term stability. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation. Store away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.