Description

6-Amino-3-Hydroxy-Pyrido[2,3-B]Pyrazine-2-Carboxylic Acid is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical advanced pharmaceutical intermediate. Its complex fused pyrido-pyrazine structure makes it a valuable building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research. This compound is essential for medicinal chemistry research and development teams, pharmaceutical manufacturers, and fine chemical suppliers focused on next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in R&D for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Oncology Drug Development: A precursor in the synthesis of experimental compounds targeting specific cancer pathways.
• Antiviral Agent Synthesis: Employed in the research and development of novel antiviral medications.
• Fine Chemical Synthesis: Serves as a specialized starting material or intermediate for other high-value, complex organic molecules.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for cGMP production of clinical trial materials.

Basic Information

Product Name	6-Amino-3-Hydroxy-Pyrido[2,3-B]Pyrazine-2-Carboxylic Acid
CAS No.	874493-62-6
Molecular Formula	C8H6N4O3
Molecular Weight	206.16 g/mol
Synonyms	6-Amino-3-hydroxypyrido[2,3-b]pyrazine-2-carboxylic acid; 2-Pyrazinecarboxylic acid, 6-amino-1,4-dihydro-3-hydroxy-1,4-dioxo-; 6-Amino-1,4-dihydro-3-hydroxy-1,4-dioxo-2-pyrazinecarboxylic acid; AHPPC; Pyrido[2,3-b]pyrazine-2-carboxylic acid, 6-amino-3-hydroxy-; 874493-62-6
EINECS	Contact for details

Quality Control

Our 6-Amino-3-Hydroxy-Pyrido[2,3-B]Pyrazine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.