Description

tert-Butyl [5-(Hydroxymethyl)Pyrazin-2-Yl]Carbamate is a high-purity, protected pyrazine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular scaffolds for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by the pharmaceutical, agrochemical, and fine chemical industries for the research and production of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used as a precursor in the development of new herbicides and fungicides with pyrazine-based active structures.
• Peptide Mimetics & PROTACs: Serves as a versatile linker or functional group in the design of peptide mimetics and Proteolysis-Targeting Chimeras (PROTACs).
• Material Science Research: Employed in the synthesis of organic ligands and functional molecules for advanced materials.
• Chemical Biology Probes: Acts as a building block for creating molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis services and contract research organizations (CROs/CMOs).

Basic Information

Product Name	tert-Butyl [5-(Hydroxymethyl)Pyrazin-2-Yl]Carbamate
CAS No.	874476-55-8
Molecular Formula	C10H15N3O3
Molecular Weight	225.25 g/mol
Synonyms	tert-Butyl N-[5-(hydroxymethyl)pyrazin-2-yl]carbamate; 2-Pyrazinecarboxamide, N-(1,1-dimethylethoxy)carbonyl-5-(hydroxymethyl)-; 5-(Hydroxymethyl)pyrazin-2-yl-carbamic acid tert-butyl ester; Boc-5-(hydroxymethyl)pyrazin-2-amine; (tert-Butoxycarbonyl)-[5-(hydroxymethyl)pyrazin-2-yl]amine; N-Boc-5-(hydroxymethyl)pyrazine-2-amine
EINECS	Contact for details

Quality Control

Our tert-Butyl [5-(Hydroxymethyl)Pyrazin-2-Yl]Carbamate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and cGMP applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.