Description

5,6,7,8-Tetrahydro-[1,2,4]Triazolo[1,5-A]Pyrazine Hydrochloride is a high-purity heterocyclic building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its role as a key precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is essential for R&D and manufacturing within the pharmaceutical, agrochemical, and advanced material science sectors.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides due to its fused triazole-pyrazine structure.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and the discovery of new biologically active molecules.
• Ligand and Catalyst Preparation: Employed in the preparation of specialized ligands for metal catalysis and coordination chemistry.
• Fine Chemical Production: Integral to multi-step synthetic routes for producing high-value, complex organic compounds.

Basic Information

Product Name	5,6,7,8-Tetrahydro-[1,2,4]Triazolo[1,5-A]Pyrazine Hydrochloride
CAS No.	874360-12-0
Molecular Formula	C6H10ClN5
Molecular Weight	187.63 g/mol
Synonyms	1,2,4-Triazolo[1,5-a]pyrazine, 5,6,7,8-tetrahydro-, hydrochloride (1:1); 5,6,7,8-Tetrahydro-1,2,4-triazolo[1,5-a]pyrazine hydrochloride; 874360-12-0; 1,2,4-Triazolo[1,5-a]pyrazine, 5,6,7,8-tetrahydro-, monohydrochloride; Tetrahydrotriazolopyrazine HCl
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-[1,2,4]Triazolo[1,5-A]Pyrazine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.