Description

1-Boc-4-(2,3-Diaminophenyl)Piperazine is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine core with a reactive diaminophenyl substituent. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecules with targeted biological activity. It is primarily utilized by pharmaceutical companies and research institutions in the synthesis of novel drug candidates, particularly in therapeutic areas requiring sophisticated heterocyclic architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for central nervous system (CNS) drugs and kinase inhibitors.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Employed in the development of molecular probes and tools for studying biological pathways and target engagement.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Library Synthesis: Utilized in combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	1-Boc-4-(2,3-Diaminophenyl)Piperazine
CAS No.	874279-78-4
Molecular Formula	C15H24N4O2
Molecular Weight	292.38 g/mol
Synonyms	1-Boc-4-(2,3-diaminophenyl)piperazine; tert-Butyl 4-(2,3-diaminophenyl)piperazine-1-carboxylate; 4-(2,3-Diaminophenyl)-N-Boc-piperazine; 1-(tert-Butoxycarbonyl)-4-(2,3-diaminophenyl)piperazine; Piperazine, 1-(1,1-dimethylethoxy)carbonyl-4-(2,3-diaminophenyl)-; 874279-78-4; BOC-2,3-DAPP
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(2,3-Diaminophenyl)Piperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.