Description

Pyrazine, 2-Chloro-3-(1,3-Dithian-2-Yl)- is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines a halogenated pyrazine core with a dithiane protecting group, making it a versatile precursor for constructing complex pharmacophores and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and infectious diseases.
• Agrochemical Synthesis: Used in the creation of advanced pesticide and herbicide molecules, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials and metal-organic frameworks (MOFs) due to its nitrogen and sulfur-containing heterocyclic structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for studying enzymatic activity and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Pyrazine, 2-Chloro-3-(1,3-Dithian-2-Yl)-
CAS No.	874114-28-0
Molecular Formula	C9H11ClN2S2
Molecular Weight	246.78 g/mol
Synonyms	2-Chloro-3-(1,3-dithian-2-yl)pyrazine; 2-Chloro-3-(1,3-dithian-2-yl)pyrazine; 1,3-Dithiane, 2-(2-chloro-3-pyrazinyl)-; 2-(2-Chloro-3-pyrazinyl)-1,3-dithiane; 2-(2-Chloropyrazin-3-yl)-1,3-dithiane; 3-Chloro-2-(1,3-dithian-2-yl)pyrazine; 874114-28-0
EINECS	Contact for details

Quality Control

Our Pyrazine, 2-Chloro-3-(1,3-Dithian-2-Yl)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.