Description

4-(3-Amino-2-Fluoro-Benzyl)-Piperazine-1-Carboxylic Acid Methyl Ester is a high-value, fluorinated piperazine derivative that serves as a critical building block in modern organic synthesis. Its molecular architecture, featuring both an aromatic amine and a piperazine ester, makes it a versatile intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new drug candidates, particularly within medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Library Synthesis: Employed in combinatorial chemistry for generating diverse compound libraries for high-throughput screening.
• Fluorinated Compound Synthesis: The fluorine atom imparts desirable metabolic stability and bioavailability, making this intermediate valuable for creating fluorinated drug candidates.
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	4-(3-Amino-2-Fluoro-Benzyl)-Piperazine-1-Carboxylic Acid Methyl Ester
CAS No.	873697-70-2
Molecular Formula	C13H18FN3O2
Molecular Weight	267.30 g/mol
Synonyms	Methyl 4-[(3-amino-2-fluorophenyl)methyl]piperazine-1-carboxylate; 1-Carbomethoxy-4-(3-amino-2-fluorobenzyl)piperazine; 4-(3-Amino-2-fluorobenzyl)piperazine-1-carboxylic acid methyl ester; 873697-70-2; 4-(3-Amino-2-fluoro-benzyl)-piperazine-1-carboxylic acid methyl ester; 1-Piperazinecarboxylic acid, 4-[(3-amino-2-fluorophenyl)methyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our 4-(3-Amino-2-Fluoro-Benzyl)-Piperazine-1-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity suitable for sensitive research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.