Description

Benzenamine, 4-(4-Ethyl-1-Piperazinyl)-3-Fluoro- is a specialized fluorinated aniline derivative featuring a substituted piperazine moiety, representing a high-value pharmaceutical intermediate. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in the development of psychoactive and neuroleptic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its fluorinated aromatic and piperazinyl functional groups.
• API Synthesis: Serves as a precursor in multi-step synthetic routes for complex active pharmaceutical ingredients.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Tool Compound: Potential use in pharmacological assays to study receptor interactions and enzyme inhibition.
• Fine Chemical Production: Intermediate for the manufacture of other specialty chemicals and advanced materials.

Basic Information

Product Name	Benzenamine, 4-(4-Ethyl-1-Piperazinyl)-3-Fluoro-
CAS No.	873537-27-0
Molecular Formula	C12H18FN3
Molecular Weight	223.29 g/mol
Synonyms	3-Fluoro-4-(4-ethylpiperazin-1-yl)aniline; 4-(4-Ethylpiperazin-1-yl)-3-fluoroaniline; 1-(2-Fluoro-4-aminophenyl)-4-ethylpiperazine; 3-Fluoro-N1-(4-ethyl-1-piperazinyl)-1,4-benzenediamine; 873537-27-0; FC-1067 (Potential research code)
EINECS	Contact for details

Quality Control

Our Benzenamine, 4-(4-Ethyl-1-Piperazinyl)-3-Fluoro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and impurities. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with customer specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture and atmospheric oxygen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.