Description

4-[(Piperidin-2-Yl)Methyl]Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected piperazine-piperidine hybrid building block of significant importance in modern pharmaceutical research and development. Its core value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly for targeting central nervous system (CNS) and other therapeutic areas. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly those targeting neurological receptors.
• Medicinal Chemistry Scaffold: Serves as a privileged structural motif for constructing libraries of compounds for high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• CNS Drug Discovery: Used in the synthesis of potential therapeutics for conditions such as depression, anxiety, schizophrenia, and neurodegenerative diseases.
• Peptidomimetic Synthesis: Acts as a constrained dipeptide surrogate or a conformational restriction element in the design of peptide-like molecules.
• Ligand for GPCRs: Employed in the research and development of ligands for G-protein coupled receptors (GPCRs), a major class of drug targets.
• Chemical Biology Probe: Utilized to create tool compounds for studying biological pathways and enzyme functions.

Basic Information

Item	Detail
Product Name	4-[(Piperidin-2-Yl)Methyl]Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	873315-23-2
Molecular Formula	C16H31N3O2
Molecular Weight	297.44 g/mol
Synonyms	1-Boc-4-[(2-piperidinyl)methyl]piperazine; tert-Butyl 4-[(piperidin-2-yl)methyl]piperazine-1-carboxylate; 4-(Piperidin-2-ylmethyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(2-piperidinylmethyl)piperazine; N-Boc-4-(2-piperidinylmethyl)piperazine; 873315-23-2; UNII-8Q6K2G0F0C
EINECS	Contact for details

Quality Control

Our 4-[(Piperidin-2-Yl)Methyl]Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.