Description

2-Cyano-3-(Pyrazin-2-Ylamino)-Acrylic Acid Ethyl Ester is a specialized organic intermediate featuring a cyanoacrylic ester core functionalized with a pyrazinylamino group. This molecular architecture makes it a valuable building block for the synthesis of complex heterocyclic compounds and functional materials. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical sectors for creating novel active ingredients and advanced chemical libraries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other biological pathways where the pyrazine scaffold is relevant.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its reactive cyanoacrylate moiety for constructing bioactive molecules.
• Organic Synthesis Building Block: Serves as a versatile reagent for constructing complex heterocycles via cyclization reactions or as a Michael acceptor in nucleophilic additions.
• Material Science Research: Potential monomer or precursor for functional polymers and advanced organic materials due to its conjugated system and multiple reactive sites.
• Chemical Library Production: Employed in combinatorial chemistry and high-throughput screening for generating diverse compound libraries in medicinal chemistry programs.

Basic Information

Product Name	2-Cyano-3-(Pyrazin-2-Ylamino)-Acrylic Acid Ethyl Ester
CAS No.	871926-02-2
Molecular Formula	C₁₁H₁₁N₅O₂
Molecular Weight	245.24 g/mol
Synonyms	Ethyl 2-cyano-3-[(pyrazin-2-yl)amino]prop-2-enoate; 2-Cyano-3-(2-pyrazinylamino)-2-propenoic Acid Ethyl Ester; (2E)-2-Cyano-3-(pyrazin-2-ylamino)acrylic Acid Ethyl Ester; Ethyl (2E)-2-cyano-3-(pyrazin-2-ylamino)acrylate; 871926-02-2; NSC 405124; AKOS015903065
EINECS	Contact for details

Quality Control

We maintain rigorous quality control protocols for all our chemical intermediates. Production follows strict internal specifications, and each batch is analyzed using advanced techniques like HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. Our quality system is designed to support cGMP and ISO-aligned manufacturing for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.