Description

1-Piperazinecarbothioamide, 4-(Tetrahydro-2H-Pyran-4-Yl)- is a high-value heterocyclic organic compound featuring a piperazine core modified with a thiocarboxamide group and a tetrahydropyran substituent. This unique structure makes it a critical pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Protease Inhibitor Development: Used in the research and synthesis of compounds designed to inhibit specific enzymes.
• Ligand Synthesis: Employed in the creation of specialized ligands for biochemical assays and receptor studies.
• Custom Synthesis Building Block: Provides a functionalized heterocyclic core for contract research organizations (CROs) and custom synthesis projects.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and protein function.

Basic Information

Item	Detail
Product Name	1-Piperazinecarbothioamide, 4-(Tetrahydro-2H-Pyran-4-Yl)-
CAS No.	871828-53-4
Molecular Formula	C10H19N3OS
Molecular Weight	229.34 g/mol
Synonyms	4-(Tetrahydro-2H-pyran-4-yl)-1-piperazinecarbothioamide; 4-(Oxan-4-yl)piperazine-1-carbothioamide; 1-Piperazinecarbothioamide, 4-(tetrahydro-2H-pyran-4-yl)-; 4-(Tetrahydropyran-4-yl)piperazine-1-carbothioamide; 871828-53-4; 4-(Oxan-4-yl)piperazine-1-carbothioamide; 4-(Tetrahydro-2H-pyran-4-yl)piperazine-1-carbothioamide
EINECS	Contact for details

Quality Control

Our production of 1-Piperazinecarbothioamide, 4-(Tetrahydro-2H-Pyran-4-Yl)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and synthesis applications. Each lot is analyzed using advanced techniques like HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.