Description

Piperazine, 1-[2-Chloro-3-(Trifluoromethoxy)Phenyl]-4-(2-Propen-1-Yl)- is a specialized, high-value piperazine derivative designed for advanced chemical synthesis. This compound matters as a key building block for developing novel active ingredients, particularly in the pharmaceutical and agrochemical sectors, where its unique trifluoromethoxy and chloro-substituted aromatic ring offers distinct biological and physicochemical properties. It is primarily needed by R&D chemists and process development scientists working on new drug candidates, crop protection agents, and other fine chemical applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of potential new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) or anti-infective targets.
• Agrochemical Research: Used as a precursor in developing next-generation herbicides, fungicides, or insecticides, leveraging the bioactivity of the trifluoromethoxy group.
• Chemical Biology Probe Development: Employed in medicinal chemistry to create tool compounds for studying biological pathways and target validation.
• Material Science Research: Acts as a monomer or functionalizing agent in the synthesis of advanced polymers with specific optical or electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise molecular fragment.

Basic Information

Product Name	Piperazine, 1-[2-Chloro-3-(Trifluoromethoxy)Phenyl]-4-(2-Propen-1-Yl)-
CAS No.	871357-04-9
Molecular Formula	C14H16ClF3N2O
Molecular Weight	320.74 g/mol
Synonyms	1-(2-Chloro-3-(trifluoromethoxy)phenyl)-4-(prop-2-en-1-yl)piperazine; 1-Allyl-4-[2-chloro-3-(trifluoromethoxy)phenyl]piperazine; N-Allyl-N'-(2-chloro-3-trifluoromethoxyphenyl)piperazine; 4-Allyl-1-(2-chloro-3-(trifluoromethoxy)phenyl)piperazine; CAS 871357-04-9
EINECS	Contact for details

Quality Control

Our Piperazine, 1-[2-Chloro-3-(Trifluoromethoxy)Phenyl]-4-(2-Propen-1-Yl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.