Description

Piperazine, 1-[2-Chloro-3-(Trifluoromethoxy)Phenyl]-4-(2-Methoxyethyl)- is a high-value, functionalized piperazine derivative designed for advanced chemical synthesis. This compound matters as a sophisticated pharmaceutical intermediate and key building block for the development of novel active ingredients. It is primarily needed by R&D chemists and process development teams in the pharmaceutical and agrochemical industries seeking to incorporate its unique trifluoromethoxy-substituted aromatic moiety into new molecular entities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the biological activity of the trifluoromethoxy group.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating tool compounds to study biological pathways and protein interactions.
• Material Science Precursor: Can be utilized in the synthesis of specialized polymers or ligands for catalysis.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and library production.

Basic Information

Product Name	Piperazine, 1-[2-Chloro-3-(Trifluoromethoxy)Phenyl]-4-(2-Methoxyethyl)-
CAS No.	871357-03-8
Molecular Formula	C14H18ClF3N2O2
Molecular Weight	338.75 g/mol
Synonyms	1-(2-Chloro-3-(trifluoromethoxy)phenyl)-4-(2-methoxyethyl)piperazine; 4-(2-Methoxyethyl)-1-[2-chloro-3-(trifluoromethoxy)phenyl]piperazine; 1-[2-Chloro-3-(trifluoromethoxy)phenyl]-4-(2-methoxyethyl)piperazine; 871357-03-8; 2-Chloro-3-(trifluoromethoxy)-1-(4-(2-methoxyethyl)piperazin-1-yl)benzene
EINECS	Contact for details

Quality Control

Our Piperazine, 1-[2-Chloro-3-(Trifluoromethoxy)Phenyl]-4-(2-Methoxyethyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.