Description

1-[2-Chloro-3-(Trifluoromethoxy)Phenyl]-4-Ethylpiperazine is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its precise molecular architecture, which serves as a critical building block in modern medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and other specialty drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting specific receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• CNS Drug Development: Serves as a core scaffold for compounds being investigated for neurological and psychiatric disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method validation in API production.
• Preclinical Studies: Used in the preparation of compounds for pharmacological and toxicological evaluation.

Basic Information

Product Name	1-[2-Chloro-3-(Trifluoromethoxy)Phenyl]-4-Ethylpiperazine
CAS No.	871357-01-6
Molecular Formula	C13H16ClF3N2O
Molecular Weight	308.73 g/mol
Synonyms	4-Ethyl-1-[2-chloro-3-(trifluoromethoxy)phenyl]piperazine; 1-(2-Chloro-3-(trifluoromethoxy)phenyl)-4-ethylpiperazine; 2-Chloro-3-(trifluoromethoxy)-N-ethylpiperazin-1-yl-benzene; 871357-01-6; 1-(2-Chloro-3-(trifluoromethoxyphenyl))-4-ethylpiperazine; 4-Ethyl-1-(2-chloro-3-trifluoromethoxyphenyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-[2-Chloro-3-(Trifluoromethoxy)Phenyl]-4-Ethylpiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for pharmaceutical R&D applications, ensuring reliable supply and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.