Description

2-Chloro-3-[4-(2-Methoxyethyl)Piperazin-1-Yl]Phenyl Methanesulfonate is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperazine-based structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), enabling the development of targeted therapeutics. It is primarily needed by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in drug discovery and process development for central nervous system (CNS) and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly those targeting neurological receptors.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in research laboratories.
• Custom Synthesis: Serves as a specialized starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• API Manufacturing: Employed in the scaled-up production of active pharmaceutical ingredients requiring a functionalized phenyl methanesulfonate moiety.
• Biochemical Research: Utilized as a tool compound in biochemical assays to study enzyme inhibition or receptor binding mechanisms.

Basic Information

Product Name	2-Chloro-3-[4-(2-Methoxyethyl)Piperazin-1-Yl]Phenyl Methanesulfonate
CAS No.	871355-77-0
Molecular Formula	C14H20ClN2O4S
Molecular Weight	356.84 g/mol
Synonyms	2-Chloro-3-[4-(2-methoxyethyl)-1-piperazinyl]phenyl methanesulfonate; Methanesulfonic acid 2-chloro-3-[4-(2-methoxyethyl)-1-piperazinyl]phenyl ester; 871355-77-0; 2-Chloro-3-(4-(2-methoxyethyl)piperazin-1-yl)phenyl methanesulfonate; 2-Chloro-3-(4-(2-methoxyethyl)piperazin-1-yl)phenyl mesylate
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-[4-(2-Methoxyethyl)Piperazin-1-Yl]Phenyl Methanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and cGMP starting material applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.