Description

Piperidine, 1-Ethyl-4-[2-Fluoro-3-(Methylsulfonyl)Phenyl]-, Hydrochloride is a high-purity, fluorinated piperidine derivative designed for advanced chemical synthesis. This compound is a critical building block in pharmaceutical research, valued for its unique structural features that enable the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for lead optimization and the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its fluorinated aromatic system for enhanced biological activity.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and receptor interactions in biochemical assays.
• Process Chemistry: Employed in route scouting and scale-up activities for the commercial manufacturing of complex organic molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific compounds under cGMP conditions.

Basic Information

Product Name	Piperidine, 1-Ethyl-4-[2-Fluoro-3-(Methylsulfonyl)Phenyl]-, Hydrochloride
CAS No.	871351-61-0
Molecular Formula	C14H20FNO2S • HCl
Molecular Weight	329.84 g/mol (Free base: 293.38 g/mol)
Synonyms	1-Ethyl-4-[2-fluoro-3-(methylsulfonyl)phenyl]piperidine hydrochloride; 4-(2-Fluoro-3-methanesulfonylphenyl)-1-ethylpiperidine hydrochloride; 871351-61-0; UNII-6V3Q8U3V4F; 6V3Q8U3V4F; 1-Ethyl-4-(2-fluoro-3-methylsulfonylphenyl)piperidine HCl; 1-Ethyl-4-(2-fluoro-3-(methylsulfonyl)phenyl)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our Piperidine, 1-Ethyl-4-[2-Fluoro-3-(Methylsulfonyl)Phenyl]-, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and KF titration for water content, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.