Description

1-Benzyl-4-(4-Chloro-[1,2,5]thiadiazol-3-yl)-piperazine is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate the unique 1,2,5-thiadiazole scaffold into new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, due to the piperazine moiety.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or insecticides where the chlorothiadiazole group can impart specific biological activity.
• Material Science: Acts as a building block for creating specialized polymers or ligands with unique electronic or binding properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function or biological pathways.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting exploratory research on heterocyclic chemistry and structure-activity relationships (SAR).

Basic Information

Product Name	1-Benzyl-4-(4-Chloro-[1,2,5]thiadiazol-3-yl)-piperazine
CAS No.	870987-93-2
Molecular Formula	C13H15ClN4S
Molecular Weight	294.80 g/mol
Synonyms	1-Benzyl-4-(4-chloro-1,2,5-thiadiazol-3-yl)piperazine; 3-(1-Benzylpiperazin-4-yl)-4-chloro-1,2,5-thiadiazole; 4-Chloro-3-(1-benzylpiperazin-4-yl)-1,2,5-thiadiazole; 870987-93-2; 1-Benzyl-4-(4-chloro-[1,2,5]thiadiazol-3-yl)piperazine; 1-Benzyl-4-(4-chloro-1,2,5-thiadiazol-3-yl)piperazine; 4-Chloro-3-(4-benzylpiperazin-1-yl)-1,2,5-thiadiazole
EINECS	Contact for details

Quality Control

Our 1-Benzyl-4-(4-Chloro-[1,2,5]thiadiazol-3-yl)-piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by IR, NMR), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.