Description

2-(4-Boc-Piperazin-1-Yl)-3-Butenoic Acid is a versatile and high-purity Boc-protected piperazine derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in providing a reactive handle for further functionalization while protecting the secondary amine, enabling the efficient synthesis of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic programs.
• Peptidomimetic Synthesis: Used to incorporate constrained piperazine scaffolds into peptide backbones to enhance metabolic stability and bioavailability.
• Combinatorial Chemistry: A valuable reagent in parallel and solid-phase synthesis for creating diverse chemical libraries for high-throughput screening.
• Agrochemical Research: Intermediate in the development of new herbicides and fungicides with novel modes of action.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and protein-protein interactions.
• Linker Chemistry: The carboxylic acid and alkene functionalities allow for conjugation to other molecules, useful in bioconjugation and materials science.

Basic Information

Product Name	2-(4-Boc-Piperazin-1-Yl)-3-Butenoic Acid
CAS No.	870703-78-9
Molecular Formula	C13H22N2O4
Molecular Weight	270.33 g/mol
Synonyms	1-Boc-4-(2-Carboxyvinyl)piperazine; 3-Butenoic acid, 2-(4-[(1,1-dimethylethoxy)carbonyl]-1-piperazinyl)-; tert-Butyl 4-(1-carboxyvinyl)piperazine-1-carboxylate; 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)but-3-enoic acid; 2-(N-Boc-piperazin-1-yl)-3-butenoic acid; Boc-Pip(Butenoic Acid); (E/Z)-2-(4-Boc-piperazin-1-yl)-3-butenoic acid
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Piperazin-1-Yl)-3-Butenoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a controlled environment to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.