Description

1-(4-Bromo-2-Fluorobenzyl)Piperazine is a high-purity, advanced pharmaceutical intermediate with the CAS number 870703-75-6. This compound is valued for its role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for neurological and psychiatric disorders.
• Agrochemical Synthesis: Used in research and development of new pesticides and herbicides due to its halogenated benzyl-piperazine structure.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic & Industrial Research: A valuable reagent for medicinal chemistry programs in both university laboratories and corporate R&D centers.

Basic Information

Product Name	1-(4-Bromo-2-Fluorobenzyl)Piperazine
CAS No.	870703-75-6
Molecular Formula	C11H14BrFN2
Molecular Weight	273.15 g/mol
Synonyms	4-Bromo-2-fluorobenzylpiperazine; 1-[(4-Bromo-2-fluorophenyl)methyl]piperazine; Piperazine, 1-[(4-bromo-2-fluorophenyl)methyl]-; 870703-75-6; 4-Bromo-2-fluoro-1-(piperazin-1-ylmethyl)benzene; 1-(4-Bromo-2-fluorobenzyl)piperazine dihydrochloride (salt form); 4-Bromo-2-fluorobenzyl piperazine; 1-(4-Bromo-2-fluoro-benzyl)-piperazine
EINECS	Contact for details

Quality Control

Our 1-(4-Bromo-2-Fluorobenzyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.