Description

4-(Boc-Piperazin-1-Yl)-3-Nitrobenzoic Acid is a high-purity, protected piperazine derivative used as a critical building block in organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex pharmaceutical molecules, particularly in medicinal chemistry and drug discovery. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on creating novel active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and combinatorial chemistry libraries to explore new therapeutic entities.
• API Development: Serves as a building block for constructing the core scaffold of potential new active pharmaceutical ingredients.
• Peptidomimetic Synthesis: Employed in the design and synthesis of peptide-like molecules with enhanced stability and bioavailability.
• Chemical Biology Probes: Useful for creating labeled or tagged molecules to study biological processes and protein interactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	4-(Boc-Piperazin-1-Yl)-3-Nitrobenzoic Acid
CAS No.	870703-72-3
Molecular Formula	C16H21N3O6
Molecular Weight	351.36 g/mol
Synonyms	3-Nitro-4-(1-Boc-piperazinyl)benzoic Acid; 4-(1-Boc-piperazin-4-yl)-3-nitrobenzoic Acid; 4-(N-Boc-piperazinyl)-3-nitrobenzoic Acid; 4-(tert-Butoxycarbonylpiperazin-1-yl)-3-nitrobenzoic Acid; 4-[(1,1-Dimethylethoxy)carbonyl]-1-piperazinyl-3-nitrobenzoic Acid; Benzoic acid, 4-[(1,1-dimethylethoxy)carbonyl]-1-piperazinyl-3-nitro-; 870703-72-3
EINECS	Contact for details

Quality Control

Our 4-(Boc-Piperazin-1-Yl)-3-Nitrobenzoic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.