Description

tert-Butyl 4-(2-(Methylsulfonyl)Ethyl)Piperazine-1-Carboxylate is a high-purity, protected piperazine derivative featuring a methylsulfonyl ethyl side chain, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), especially within therapeutic areas requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis due to its reactive piperazine core and sulfone functionality.
• Process Chemistry & Scale-up: Employed in the development and optimization of scalable synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Ligand & Catalyst Development: Serves as a starting material for creating novel ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Synthesis: Potential intermediate in the research and development of new crop protection agents and herbicides.
• Material Science: Can be utilized in the synthesis of specialty polymers and functional materials requiring specific nitrogen-based monomers.

Basic Information

Product Name	tert-Butyl 4-(2-(Methylsulfonyl)Ethyl)Piperazine-1-Carboxylate
CAS No.	870007-74-2
Molecular Formula	C12H24N2O4S
Molecular Weight	292.40 g/mol
Synonyms	1-Boc-4-(2-(Methylsulfonyl)ethyl)piperazine; tert-Butyl 4-[2-(Methylsulfonyl)ethyl]piperazine-1-carboxylate; 4-(2-(Methylsulfonyl)ethyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(2-(methylsulfonyl)ethyl)piperazine; N-Boc-4-(2-(Methylsulfonyl)ethyl)piperazine; BOC-Piperazine-ESO2Me; Piperazine, 4-[2-(methylsulfonyl)ethyl]-, 1-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-(Methylsulfonyl)Ethyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.