Description

1,3-Diarachidonoyl-2-Oleoyl Glycerolol is a structured triacylglycerol (TAG) featuring a specific arrangement of arachidonic acid (AA) and oleic acid (OA) on the glycerol backbone. This precise molecular architecture is critical for research into lipid metabolism, signaling pathways, and the development of specialized lipid-based formulations. It serves as a high-purity reference standard and a key synthetic intermediate for advanced studies in biochemistry, nutrition, and pharmaceutical sciences, where the positional distribution of fatty acids dictates biological function and stability.

Application

• Biochemical Research Standard: Used as a high-purity reference material for the analysis and quantification of complex lipids in biological samples via LC-MS or GC-MS.
• Lipidomics & Metabolomics: Serves as a critical standard for mapping lipid pathways and understanding the role of specific triacylglycerol species in cellular processes.
• Pharmaceutical Excipient Development: Investigated for use in advanced drug delivery systems, such as lipid nanoparticles (LNPs) and self-emulsifying drug delivery systems (SEDDS), due to its unique fatty acid profile.
• Nutritional Science: Employed in studies examining the metabolic fate, absorption, and health impacts of structured lipids with defined fatty acid positioning.
• Synthetic Intermediate: Acts as a building block for the chemical or enzymatic synthesis of more complex, labeled, or conjugated lipid molecules for diagnostic and therapeutic research.
• Cell Culture & In Vitro Studies: Used to supplement media in studies focused on eicosanoid production, membrane fluidity, and the effects of specific lipid structures on cell function.

Basic Information

Item	Details
Product Name	1,3-Diarachidonoyl-2-Oleoyl Glycerolol
CAS No.	869990-37-4
Molecular Formula	C65H104O6
Molecular Weight	981.53 g/mol
Synonyms	1,3-Di(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-(9Z-octadecenoyl)-glycerol; TAG 20:4/18:1/20:4; AA-OA-AA Triglyceride; Glycerol, 1,3-bis(5Z,8Z,11Z,14Z-eicosatetraenoate)-2-(9Z)-9-octadecenoate; Structured Triglyceride (AA,OA,AA); 1,3-Diarachidonin-2-olein; 1,3-Bis(all-cis-5,8,11,14-eicosatetraenoyl)-2-oleoyl-rac-glycerol
EINECS	Contact for details

Quality Control

Our 1,3-Diarachidonoyl-2-Oleoyl Glycerolol is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and development standards, and specifications can be aligned with customer-specific requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow oily liquid
Identification (HPLC/MS)	Conforms to structure
Assay (HPLC)	≥ 95% (Area Percent)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Peroxide Value	≤ 5.0 meq/kg
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.